CURRICULUM VITAE

Thomas M. Freeland

Date of Birth:November 30, 1957

Place of Birth:Wheeling, WV

Personal Information:married Denise Hough, June 1987

son Conor, born May 1992

son Duncan, born December 1996

Degrees Held:  B.S., Biology (West Liberty State College, West Liberty, West Virginia, May 1980)

M.S., Genetics and Developmental Biology (West Virginia University, Morgantown, West Virginia, August 1988)

Ph.D., Pharmacology and Toxicology (West Virginia University School of Medicine, December 1991)

EMPLOYMENT:

1995-present:Associate Professor of Biology, Walsh University, 2020 Easton St, North Canton, OH, 44720. Teaching a wide variety of biology courses, advising undergraduates, and conducting research in various biological and biomedical topics, with the involvement of undergraduate students.

1995:Adjunct Professor of Biology, Penn State University Post-Baccalaureate Pre-Med Program; taught General Biology to beginning students in this program. Post-doctoral researcher in Penn State Department of Anthropology; worked on mapping of the chromosomal region containing the important mammalian developmental gene dlx-7.

1991-1995:Post-doctoral Scholar, Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA16802. Engaged in research projects with Dictyostelium discoideuminvolving DNA damage and repair in the nuclear genome, mitochondrial genome, and individual genes; also cloning and sequencing of DNA repair-related genes

1988-1991:Graduate Assistant, Dept. of Pharmacology and Toxicology, West Virginia University Health Sciences Center, Morgantown WV 26506. Involved lecturing to Nursing students and working with Medical students in small study groups, in addition to doing original research, indicated in abstracts and publications below

1987-1988:Lecturer in Human Genetics, Fayette Campus of Penn State University, design and teaching of the Biology 33 course for 25-40 undergraduate students per semester

1984-1987:Teaching Assistant, Dept. of Biology, West Virginia University, which involved instructing undergraduate laboratories in General Biology and Comparative Anatomy

1981-1984:Counselor, Community Mental Health Services, Bellaire City Hospital, Bellaire OH, which involved counseling mental health patients in the Psychiatric unit of City Hospital, as well as intervening in psychiatric emergencies in the community, along with police, EMS technicians, and social workers

1980-1981:Laboratory Technician in organic chemistry, U.S. Environmental Protection Agency, Wheeling, WV; involving analysis of water, soil, and tissue samples for the presence of pesticides and PCB's via organic extraction and gas chromatography

HONORS:

1980:Honors graduate, 1980; Outstanding Biology Student, 1979-80; Outstanding Peer Counselor, 1979-80 (as a tutor in chemistry, physics, biology, and Shakespeare); West Liberty State College

1988 and 1990:NIH Training Grant in Pharmacology

1989:Fellowship for Graduate Research from Berlex Laboratories, Cedar Knolls, NJ

1990-91:Student Representative in Pharmacology and Toxicology; presenting student concerns at faculty meetings, coordinating student activities (e.g. invited speakers, student meetings, etc.), acted as Student Representative from the Basic Sciences at joint meetings of all colleges within the School of Medicine

DISSERTATION ADVISOR:Jeannine S. Strobl, Ph.D., Professor of Pharmacology and Toxicology, West Virginia University School of Medicine

POST-DOCTORAL MENTOR:Reginald A. Deering, Ph.D., Professor of Biochemistry and Biophysics, The PennsylvaniaState University

RESEARCH INTERESTS:DNA sequences involved in control of replication and/or gene expression; relationship of DNA secondary structure and topology to gene function; chromatin structure and its relationship to gene function; mechanisms of DNA repair and the relationship of DNA repair and replication processes; genetic toxicology; molecular biology as a tool for understanding mechanisms of genetic toxicology; investigating the activation of transcription in DNA repair genes; human genetics and disease-causing mutations of the human genome.

PUBLICATIONS

Abstracts 

Freeland, T.M. and Strobl, J.S. (1988). Unusual Sequences Upstream of the Rat Growth Hormone Gene Promoter. The Journal of Cell Biology 107, 6, Abstract #4293.

Freeland, T.M., and R.A. Deering (1992). Bleomycin-induced single- and double-strand breaks in extrachromosomal, mitochondrial, and nuclear main band DNA in Dictyostelium discoideum.Special meeting of the American Association for Cancer Research, "Chemicals, Mutations, and Cancer," December 1992, Banff,Alberta, Canada.

Freeland, T.M., Guyer, R.B., and Deering, R.A. (1994). Exploring the induction of DNA repair in Dictyostelium discoideum by mRNA analysis, cloning, and PCR. International Dictyostelium Conference, August 1994, University of California, San Diego.

Freeland, T.M. (1998). DNA repair systems in Dictyostelium discoideum. Invited presentation to the West Virginia University Genetics and Developmental Biology Program, June 1998.

Hoeprich, S., and Freeland, T. (2001). A Systematic Method for the Ordering of Restriction Sites on a DNA Fragment.Annual Meeting of the Ohio Academy of Science, March 31, 2001, at Mt. Union College, Alliance, OH.

Papers

Droy, B.F., Miller, M.R., Freeland, T.M., and Hinton, D.E. (1988). Immunohistochemical detection of CCl4-induced, mitosis-related DNA synthesis in livers of trout and rat. Aquatic Toxicology 13, 155-166.

Thomas, M.J., Freeland, T.M., and Strobl, J.S. (1990). Z-DNA Formation in the Rat Growth Hormone Gene Promoter Region. Molecular andCellular Biology 10, 5378-5387.

Mauldin, S.K., Freeland, T.M., and Deering, R.A. (1994). Differential repair of UV damage in a developmentally regulated gene of Dictyostelium discoideum. Mutation Research 314, 187-198.

Freeland, T.M., Guyer, R.B., Ling, A.Z., and Deering, R.A. (1996).Apurinic/apyrimidinic (AP) endonuclease from Dictyostelium discoideum: cloning, nucleotide sequence, and induction by sublethal levels of DNA damaging agents. NucleicAcids Research 24, 1950-1953.

Nakamura, S., Stock, D., Wydner, K., Bollekens, J., Takeshita, K., Nagai, B.,Chiba, S., Kitamura, T., Freeland, T., Zhao, Z., Minowada, J., Lawrence, J., Weiss, K., and Ruddle, F. (1996). Genomic analysis of a new mammalian distal-less gene: Dlx7. Genomics 38, 314-324.

Articles

"The Genes 'R' Us Fallacy," in Ways of Seeing: Foundations of Interdisciplinary Study, Tapestry Press, Ltd., 1999.

"A Scientist Responds to Some Creationist Claims," in Ways of Seeing Foundations of Interdisciplinary Study, Tapestry Press, Ltd., 1999.

"What is Science?" in Ways of Seeing Foundations of Interdisciplinary Study, Tapestry Press, Ltd., 1999.